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Fluensulfone

Cat. No. M9728
Fluensulfone Structure
Synonym:

MCW-2

Size Price Availability
5mg USD 150 4-7 Days
10mg USD 265 4-7 Days
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 291.70
Formula C7H5ClF3NO2S2
CAS Number 318290-98-1
Purity >99%
Solubility DMSO ≥ 60 mg/mL
Storage at -20°C
References

Efficacy of Various Application Methods of Fluensulfone for Managing Root-knot Nematodes in Vegetables
Kelly A Morris, et al. J Nematol. 2016 Jun;48(2):65-71. PMID: 27418698.

Fluensulfone is a nematicide with a mode of action distinct from anticholinesterases and macrocyclic lactones
James Kearn, et al. Pestic Biochem Physiol. 2014 Feb;109:44-57. PMID: 24581383.

Relationship of metabolism and cell proliferation to the mode of action of fluensulfone-induced mouse lung tumors: analysis of their human relevance using the IPCS framework
Christian Strupp, et al. Toxicol Sci. 2012 Jul;128(1):284-94. PMID: 22491425.

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