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Flubendazole

Cat. No. M5649
Flubendazole Structure
Synonym:

Flumoxanal, NSC 313680

Size Price Availability Quantity
100mg USD 60 In stock
500mg USD 90 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Flubendazole is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 313.28
Formula C16H12FN3O3
CAS Number 31430-15-6
Purity >99%
Solubility 3 mg/mL warmed in DMSO
Storage at -20°C
References

Flubendazole, FDA-approved anthelmintic, targets breast cancer stem-like cells.
Hou ZJ, et al. Oncotarget. 2015 Mar 20;6(8):6326-40. PMID: 25811972.

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Keywords: Flubendazole, Flumoxanal, NSC 313680 supplier, Autophagy, inhibitors

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