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FITC-Dextran(MW 40000)

Cat. No. M21428
FITC-Dextran(MW 40000) Structure
Size Price Availability Quantity
5mg USD 130  USD130 In stock
10mg USD 210  USD210 In stock
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Quality Control
  • Current batch:
  • Purity MW. ~40000
  • COA
  • MSDS
Biological Activity

FITC-Dextran is a marker consisting of coupling fluorescein-isothiocyanate to dextran.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight
Formula
CAS Number 60842-46-8
Purity MW. ~40000
Solubility Water ≥ 30 mg/mL
Storage 4°C, protect from light, dry, sealed
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