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Fendiline HCl

Cat. No. M5640
Fendiline HCl Structure
Size Price Availability Quantity
100mg USD 65 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Fendiline is a nonselective calcium channel blocker.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 351.91
Formula C23H26ClN
CAS Number 13636-18-5
Purity >99%
Solubility 30 mg/mL in DMSO
Storage at -20°C
References

Effects of fendiline on cocaine-seeking behavior in the rat.
Cunningham JJ, et al. Psychopharmacology (Berl). 2015 Dec;232(24):4401-10. PMID: 26345344.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Fendiline HCl supplier, Calcium Channel, inhibitors

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