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FDA-approved Drug Library

Cat. No. MS1020
FDA-approved Drug Library Structure
Synonym:

Screening Library Libraries

Size Price Availability
100 μL/well (10mM solution) USD 7152 Custom Synthesis
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Quality Control
Biological Activity

• A unique collection of 1787 FDA approved drugs for HTS and HCS.
• Approach new targets for old drugs.
• Bioactivity and safety verified by preclinical research and clinical trials.
• FDA authentication of all compounds.
• Oncology, cardiology, anti-inflammatory, immunology, neuropsychiatry, analgesia etc are concerned.
• Structurally diverse, medicinally active, and cell permeable.
• Abundant documentation with structure, IC50, and customer reviews.
• Quality inspection report of NMR and HPLC ensure high purity.
• All compounds are in stock.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight
Formula
CAS Number
Purity 1787
Solubility
Storage at -20°C
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Keywords: FDA-approved Drug Library, Screening Library Libraries supplier, Screening Libraries, inhibitors

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