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Etonogestrel

Cat. No. M5635

Etonogestrel Structure

Synonym: Implanon, Nexplanon, 3-Oxodesogestrel, 3-keto-Desogestrel

Size Price Availability Quantity
5mg USD 60 In stock
10mg USD 77 In stock
50mg USD 310 In stock
100mg USD 480 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Etonogestrel is a synthetic form of the naturally occurring female sex hormone progesterone. It binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 324.46
Formula C22H28O2
CAS Number 54048-10-1
Purity >99%
Solubility 64 mg/mL in DMSO
Storage at -20°C
References

Use of the etonogestrel implant and levonorgestrel intrauterine device beyond the U.S. Food and Drug Administration-approved duration.
McNicholas C, et al. Obstet Gynecol. 2015 Mar;125(3):599-604. PMID: 25730221.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Etonogestrel, Implanon, Nexplanon, 3-Oxodesogestrel, 3-keto-Desogestrel supplier, Estrogen Receptor, inhibitors

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