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Epinastine

Cat. No. M5615
Epinastine Structure
Size Price Availability Quantity
50mg USD 95 In stock
100mg USD 160 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Epinastine(WAL801) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 249.31
Formula C16H15N3
CAS Number 80012-43-7
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C
References

Efficacy of epinastine hydrochloride ophthalmic solution in allergic conjunctivitis by conjunctival cedar pollen allergen challenge.
Fujishima H, et al. Ann Allergy Asthma Immunol. 2014 Oct;113(4):476-81. PMID: 25163405.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Epinastine supplier, Histamine Receptor, inhibitors

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