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Dicyandiamide

Cat. No. M9401
Dicyandiamide Structure
Synonym:

Cyanoguanidine

Size Price Availability Quantity
25g USD 25  USD25 In stock
100g USD 30  USD30 In stock
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Quality Control & Documentation
Biological Activity

Dicyandiamide is a nitrification inhibitor that is said to be capable of reducing nitrate (NO3-) leaching and nitrous oxide (N2O) emissions from grazed pasture soils.

Chemical Information
Molecular Weight 84.08
Formula C2H4N4
CAS Number 461-58-5
Solubility (25°C) Soluble in warmed water ~30mg/mL
Storage 4°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yu-Pin Lin, et al. Measuring Responses of Dicyandiamide-, 3,4-Dimethylpyrazole Phosphate-, and Allylthiourea-Induced Nitrification Inhibition to Soil Abiotic and Biotic Factors

[2] Saisai Chen, et al. Dicyandiamide-assisted HKUST-1 derived Cu/N-doped porous carbon nanoarchitecture for electrochemical detection of acetaminophen

[3] Yue You, et al. Effects of dicyandiamide on cadmium accumulation in pakchoi under instant soluble nitrogen fertilizers

[4] Yanhui Zhao, et al. Interactions between dicyandiamide and periphytic biofilms in paddy soils and subsequent effects on nitrogen cycling

[5] Jianfeng Ning, et al. Dicyandiamide has more inhibitory activities on nitrification than thiosulfate

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Keywords: Dicyandiamide, Cyanoguanidine supplier, inhibitors, activators


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