Dibucaine is a local anesthetic of the amide type now generally used for surface anesthesia.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||36 mg/mL in DMSO|
A competitive strategy based on cucurbituril supramolecular interaction for simple and sensitive detection of dibucaine.
Li Y, et al. Talanta. 2015 Jan;132:653-7. PMID: 25476359.
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