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Dibucaine

Cat. No. M5570
Dibucaine Structure
Synonym:

Cinchocaine

Size Price Availability Quantity
100mg USD 80 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Dibucaine is a local anesthetic of the amide type now generally used for surface anesthesia.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 343.46
Formula C20H29N3O2
CAS Number 85-79-0
Purity >98%
Solubility 36 mg/mL in DMSO
Storage at -20°C
References

A competitive strategy based on cucurbit[7]uril supramolecular interaction for simple and sensitive detection of dibucaine.
Li Y, et al. Talanta. 2015 Jan;132:653-7. PMID: 25476359.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Dibucaine, Cinchocaine supplier, Sodium Channel, inhibitors

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