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Daunorubicin hydrochloride

Cat. No. M2327
Daunorubicin hydrochloride Structure
Synonym:

Daunomycin hydrochloride

Size Price Availability Quantity
10mg USD 60 In stock
50mg USD 160 In stock
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Quality Control
Biological Activity

Daunorubicin hydrochloride inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 563.98
Formula C27H29NO10.HCl
CAS Number 23541-50-6
Purity 99.93%
Solubility DMSO 100 mg/mL
Water 100 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Daunorubicin hydrochloride, Daunomycin hydrochloride supplier, DNA/RNA Synthesis, inhibitors

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