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D-Pantothenic acid

Cat. No. M5596
D-Pantothenic acid Structure
Synonym:

pantothenate; vitamin B5

Size Price Availability Quantity
100mg USD 59  USD59 In stock
500mg USD 88  USD88 In stock
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Quality Control & Documentation
Biological Activity

D-Pantothenic acid(pantothenate) is a water-soluble vitamin and an essential nutrient for for many animals.

Chemical Information
Molecular Weight 219.24
Formula C9H17NO5
CAS Number 79-83-4
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Shibata K, et al. J Nutr Sci Vitaminol (Tokyo). D-pantethine has vitamin activity equivalent to d-pantothenic acids for recovering from a deficiency of D-pantothenic acid in rats.

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Keywords: D-Pantothenic acid, pantothenate; vitamin B5 supplier, Vitamin, inhibitors, activators


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