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D-Mannose

Cat. No. M9226
D-Mannose Structure
Size Price Availability Quantity
100mg USD 35  USD35 In stock
500mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylation of specific proteins.

Product Citations
Chemical Information
Molecular Weight 180.16
Formula C6H12O6
CAS Number 3458-28-4
Solubility (25°C) Water: ≥ 60 mg/mL
Storage 4°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Genovese C, et al. J Chemother. Effects of a new combination of plant extracts plus d-mannose for the management of uncomplicated recurrent urinary tract infections.

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