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Cyclic Pifithrin-α hydrobromide

Cat. No. M8014
Cyclic Pifithrin-α hydrobromide Structure
Synonym:

Cyclic Pifithrin-α hydrobromide; Cyclic PFT-α hydrobromide; PFT-β hydrobromide

Size Price Availability Quantity
10mg USD 100 In stock
50mg USD 360 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

A stable analog of Pifithrin-α (Product Code P4359) with similar biological activities and lower cellular toxicity.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 349.29
Formula C16H16N2S · HBr
CAS Number 511296-88-1
Purity >98%
Solubility DMSO: 20 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Cyclic Pifithrin-α hydrobromide, Cyclic Pifithrin-α hydrobromide; Cyclic PFT-α hydrobromide; PFT-β hydrobromide supplier, Mdm2, inhibitors

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