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Cat. No. M5261
CP21R7 Structure


Size Price Availability Quantity
5mg USD 150 In stock
10mg USD 240 In stock
50mg USD 780 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

CP21R7 can inhibitor enhances the induction of KDR+precursors prior to vascular commitment.Cp21R7 compound induced the highest luciferase activity at a concentration of 3 μ M. Immunofluorescence staining revealed that CP21 significantly increased total levels of intracellular -catenin. Activation of WNT signaling via GSK3 inhibition with CP21 induced commitment of hPSCs towards mesoderm.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 317.34
Formula C19H15N3O2
CAS Number 125314-13-8
Purity >98%
Solubility 63 mg/mL in DMSO
Storage at -20°C

Manipulation of a VEGF-Notch signaling circuit drives formation of functional vascular endothelial progenitors from human pluripotent stem cells.
Sahara M, et al. Cell Res. 2015 Jan;25(1):148. PMID: 25553820.

Vaccination with vascular progenitor cells derived from induced pluripotent stem cells elicits antitumor immunity targeting vascular and tumor cells.
Koido S, et al. Cancer Immunol Immunother. 2014 May;63(5):459-68. PMID: 24627093.

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Abmole Inhibitor Catalog 2017

Keywords: CP21R7, CP21 supplier, Wnt/beta-catenin, inhibitors

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