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Clopidogrel

Cat. No. M3280
Clopidogrel Structure
Synonym:

SR-25990C

Size Price Availability Quantity
100mg USD 60 In stock
1g USD 110 In stock
500mg USD 140 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Clopidogrel (Plavix) is an oral, thienopyridine class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. Clopidogrel works by irreversibly inhibiting a receptor called P2Y12, an adenosine diphosphate ADP chemoreceptor.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 321.82
Formula C16H16ClNO2S
CAS Number 113665-84-2
Purity >99%
Solubility 84 mg/mL in DMSO
Storage at -20°C
References

Proton pump inhibitor and clopidogrel interaction: fact or fiction?
Laine L,et.al. Am J Gastroenterol. 2010 Jan;34-41. PMID: 19904241.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Clopidogrel, SR-25990C supplier, P2 Receptor, inhibitors

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