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Clebopride malate

Cat. No. M5525
Clebopride malate Structure
Size Price Availability Quantity
10mg USD 80 In stock
50mg USD 180 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 507.96
Formula C24H30ClN3O7
CAS Number 57645-91-7
Purity >98%
Solubility 34 mg/mL in DMSO
Storage at -20°C
References

A case of respiratory dyskinesia due to clebopride malate
Kawasaki H, et al. Rinsho Shinkeigaku. 1991 Aug;31(8):878-81. PMID: 1764865.

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  Catalog
Abmole Inhibitor Catalog 2017




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