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Cilofexor

Cat. No. M9039
Cilofexor Structure
Synonym:

GS-9674; PX-104

Size Price Availability Quantity
10mg USD 250 In stock
50mg USD 840 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Cilofexor is a farnesoid X receptor (FXR) agonist.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 552.4
Formula C28H23Cl2N3O5
CAS Number 1418274-28-8
Purity >98%
Solubility DMSO 10 mM
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Cilofexor, GS-9674; PX-104 supplier, Farnesoid X Receptor, inhibitors

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