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Chlorotoxin TFA

Cat. No. M14207
Chlorotoxin TFA Structure
Synonym:

TFA

Size Price Availability Quantity
1mg USD 600  USD600 In stock
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Quality Control & Documentation
Biological Activity

Chlorotoxin TFA is a peptide isolated from the venom of the scorpion Leiurus quinquestriatus, acts as a chloride channel blocker. Anti-cancer activity.

Chemical Information
Molecular Weight 4109.74
CAS Number 163515-35-3 (free base)
Solubility (25°C) Water 12.5 mg/mL
Storage -20°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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  Catalog
Abmole Inhibitor Catalog




Keywords: Chlorotoxin TFA, TFA supplier, Chloride Channel, inhibitors, activators


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