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CGS 21680 hydrochloride

Cat. No. M2282
CGS 21680 hydrochloride Structure
Size Price Availability Quantity
10mg USD 160 In stock
25mg USD 320 In stock
50mg USD 580 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

CGS 21680 hydrochloride is an A2A adenosine receptor agonist with Ki of 27 nM. It has affinity for A1 and A3 adenosine receptors but can be used to distinguish A2A- and A2B-mediated effects.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 535.98
Formula C23H29N7O6.HCl
CAS Number 124431-80-7
Purity >99%
Solubility DMSO 80 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




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