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Camelliaside A

Cat. No. M10662
Camelliaside A Structure
Size Price Availability Quantity
2mg USD 250  USD250 In stock
5mg USD 400  USD400 In stock
10mg USD 650  USD650 In stock
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Quality Control & Documentation
Biological Activity

Camelliaside A is a flavonoid from the methanol extract of tea (Camellia oleifera) seed pomace.

Chemical Information
Molecular Weight 756.66
Formula C33H40O20
CAS Number 135095-52-2
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Aleksandar Shkondrov, et al. Nat Prod Res. A new tetracyclic saponin from Astragalus glycyphyllos L. and its neuroprotective and hMAO-B inhibiting activity

[2] Dae-won Chung, et al. J Sci Food Agric. Novel synthesis of leucoside by enzymatic hydrolysis of tea seed extract

[3] Hyang-Bok Lee, et al. J Sci Food Agric. Isolation and anti-inflammatory effect of astragalin synthesized by enzymatic hydrolysis of tea seed extract

[4] Hyang-Bok Lee, et al. J Agric Food Chem. Isolation and characterization of nicotiflorin obtained by enzymatic hydrolysis of two precursors in tea seed extract

[5] T Sekine, et al. Chem Pharm Bull (Tokyo). Isolation of camelliaside C from "tea seed cake" and inhibitory effects of its derivatives on arachidonate 5-lipoxygenase

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