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Calcitonin salmon is a calcium-regulating hormone that is a dual agonist of amylin and calcitonin receptors that stimulate bone production and inhibit bone resorption.
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Molecular Weight | 3431.85 |
| Formula | C145H240N44O48S2 |
| CAS Number | 47931-85-1 |
| Purity | >98% |
| Solubility | Water ≥ 60 mg/mL |
| Storage | at -20°C |
[1] Akash Srinivasan, et al. J Musculoskelet Neuronal Interact. Calcitonin: A useful old friend
[2] P M Sexton, et al. Curr Med Chem. Calcitonin
[3] A Itabashi. Nihon Rinsho. [Calcitonin]
[4] J Y Reginster. Rev Med Liege. [Calcitonin]
[5] J T Potts Jr, et al. Curr Top Exp Endocrinol. Calcitonin
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