Bromhexine HCl is a medication prescribed for coughs which works by dissolving hard phlegm.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||6 mg/mL in DMSO|
Solubility and solution stability studies of different amino acid prodrugs of bromhexine.
Aggarwal AK, et al. Drug Dev Ind Pharm. 2012 Nov;38(11):1319-27. PMID: 22283553.
|Dimethyl succinate (Standard for GC)
Dimethyl succinate is a biodegradable ester with low odor and low volatility and commonly serves as a flavoring agent that can be used in perfumery and personal are products, including skin-conditioning agents and emollient.
Sodium bicarbonate is an inorganic salt used as a buffering agent and a pH adjuster, it also serves as a neutralizer.
Proglumide is a nonpeptide and orally active cholecystokinin (CCK)-A/B receptors antagonist.
Fmoc-Asn(Trt)-OPfp is a non-essential amino acid.
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