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Bisoprolol fumarate

Cat. No. M5462
Bisoprolol fumarate Structure
Synonym:

EMD33512

Size Price Availability Quantity
100mg USD 70 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Bisoprolol fumarate is a selective type β1 adrenergic receptor blocker.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 441.52
Formula C22H35NO8
CAS Number 104344-23-2
Purity >99%
Solubility 88 mg/mL in DMSO
Storage at -20°C
References

Spectrophotometric method for estimation of bisoprolol fumarate in tablets.
Panainte AD, et al, Rev Med Chir Soc Med Nat Iasi. 2014 Apr-Jun;118(2):558-63. PMID: 25076731.

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  Catalog
Abmole Inhibitor Catalog 2017




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