Free shipping on all orders over $ 500

Biocytin

Cat. No. M6509
Biocytin Structure
Synonym:

(+)-Biocytin

Size Price Availability Quantity
10mg USD 75  USD75 In stock
50mg USD 120  USD120 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Biocytin is a versatile marker used in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays. Displays high solubility in aqueous solutions and has a low molecular weight facilitating injection using micropipettes. Can be incorporated with a variety of avidin and streptavidin conjugates for detection by light, fluorescence or electron microscope.

Chemical Information
Molecular Weight 372.48
Formula C16H28N4O4S
CAS Number 576-19-2
Form Solid
Solubility (25°C) Water 18.62 mg/mL (with gentle warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Palomer, et al. J Med Chem. Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models.

Related Metabolite/Endogenous Metabolite Products
Biliverdin

Biliverdin is the product of the oxidation of bilirubin. Biliverdin can be synthesized via a non-protoporphyrin pathway in Corynebacterium glutamicum.

Stachyose hydrate

Stachyose tetrahydrate is a functional oligosaccharide, acts as a prebiotic. Stachyose tetrahydrate can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine. Stachyose hydrate exhibit a hypoglycemic effect, and improve inflammation through modulating gut microbiota.

Stachyose tetrahydrate

Stachyose tetrahydrate is a functional oligosaccharide, acts as a prebiotic. Stachyose tetrahydrate can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine.

1-Methylxanthine

1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.

Mannan

Mannan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  Catalog
Abmole Inhibitor Catalog




Keywords: Biocytin, (+)-Biocytin supplier, Metabolite/Endogenous Metabolite, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.