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Bezafibrate

Cat. No. M2455
Bezafibrate Structure
Synonym:

BM15075

Size Price Availability Quantity
200mg USD 120 In stock
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Quality Control
Biological Activity

Bezafibrate is the first clinically tested dual and pan-PPAR co-agonism.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 361.82
Formula C19H20ClNO4
CAS Number 41859-67-0
Purity 100.00%
Solubility DMSO 58 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Bezafibrate, BM15075 supplier, PPAR, inhibitors

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