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Benzocaine hydrochloride

Cat. No. M5449

Benzocaine hydrochloride Structure
Size Price Availability Quantity
100mg USD 100 In stock
500mg USD 300 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Benzocaine hydrochloride is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 201.65
Formula C9H11NO2.HCl
CAS Number 23239-88-5
Purity >99%
Solubility 40 mg/mL in DMSO
Storage at -20°C
References

Using topical benzocaine before lingual frenotomy did not reduce crying and should be discouraged.
Ovental A, et al. Acta Paediatr. 2014 Jul;103(7):780-2. PMID: 24724835.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Benzocaine hydrochloride supplier, Sodium Channel, inhibitors

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