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Beclometasone dipropionate

Cat. No. M5446
Beclometasone dipropionate Structure
Size Price Availability Quantity
500mg USD 120 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 521.04
Formula C28H37ClO7
CAS Number 5534-09-8
Purity >99%
Solubility 104 mg/mL in DMSO
Storage at -20°C
References

Real-life comparison of beclometasone dipropionate as an extrafine- or larger-particle formulation for asthma.
Price D, et al, Respir Med. 2013 Jul;107(7):987-1000. PMID: 23643486.

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