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Bambuterol hydrochloride

Cat. No. M3662
Bambuterol hydrochloride Structure
Synonym:

KWD-2183; (¡À)-Bambuterol hydrochlorid

Size Price Availability Quantity
10mM*1mL In DMSO USD 60 In stock
10mg USD 60 In stock
50mg USD 90 In stock
100mg USD 120 In stock
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Quality Control
Biological Activity

Bambuterol hydrochloride is a potent β2-adrenoceptor agonist. Bambuterol hydrochloride is a selective butyrylcholinesterase inhibitor. Bambuterol hydrochloride shows bronchodilatory and anti-allodynic effects in vivo. Bambuterol hydrochloride is orally active.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 403.90
Formula C18H29N3O5.HCl
CAS Number 81732-46-9
Purity >98%
Solubility DMSO
Storage at -20°C
References

Effects of bambuterol and terbutaline on isolated rat's tracheal smooth muscle.
Chou YL, et al. Eur Arch Otorhinolaryngol. 2010 Aug;267(8):1305-11. PMID: 20012638.

Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol.
Bosak A, et al. Arch Biochem Biophys. 2008 Mar 1;471(1):72-6. PMID: 18167304.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Bambuterol hydrochloride, KWD-2183; (¡À)-Bambuterol hydrochlorid supplier, Adrenergic Receptor, inhibitors

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