Free shipping on all orders over $ 500

Balofloxacin

Cat. No. M5443
Balofloxacin Structure
Size Price Availability Quantity
100mg USD 65  USD65 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Balofloxacin is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.

Chemical Information
Molecular Weight 389.42
Formula C20H24FN3O4
CAS Number 127294-70-6
Solubility (25°C) 5 mg/mL in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Jiang H, et al. J Ocul Pharmacol Ther. In vitro and in vivo effectiveness evaluation of balofloxacin in experimental Staphylococcus aureus keratitis.

Related Topoisomerase Products
ICRF-193

ICRF-193 is an TopoII inhibitor.

Topoisomerase II inhibitor 15

Topoisomerase II inhibitor 15 is a Topoisomerase II inhibitor.

Topoisomerase II inhibitor 13

Topoisomerase II inhibitor 13 is a topoisomerase II (Topo II) inhibitor.

ICRF-196

ICRF-196 is an racemic mixture of the (S,S)- and (R,R)-isomers of ICRF-193.

Cholesteryl hemisuccinate

Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity.

  Catalog
Abmole Inhibitor Catalog




Keywords: Balofloxacin supplier, Topoisomerase, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.