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Balofloxacin

Cat. No. M5443
Balofloxacin Structure
Size Price Availability Quantity
100mg USD 70 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Balofloxacin is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 389.42
Formula C20H24FN3O4
CAS Number 127294-70-6
Purity >99%
Solubility 5 mg/mL in DMSO
Storage at -20°C
References

In vitro and in vivo effectiveness evaluation of balofloxacin in experimental Staphylococcus aureus keratitis.
Jiang H, et al. J Ocul Pharmacol Ther. 2014 Aug;30(6):482-8. PMID: 24828089.

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  Catalog
Abmole Inhibitor Catalog 2017




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