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AZD7687

Cat. No. M2722
AZD7687 Structure
Size Price Availability Quantity
5mg USD 220 In stock
25mg USD 780 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

GlcNAcstatin inhibits a bacterial O-GlcNAcase (bOGA) with a Ki of 4.6 pM, inhibits human O-GlcNAcase (hOGA) with Ki of 4.4 nM, exhibits 164-fold selectivity over HexA/B.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 367.44
Formula C21H25N3O3
CAS Number 1166827-44-6
Purity >99%
Solubility DMSO
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: AZD7687 supplier, Transferase, inhibitors

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