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Atropine Sulfate Monohydrate

Cat. No. M5433
Atropine Sulfate Monohydrate  Structure
Synonym:

Atropine sulfate hydrate

Size Price Availability Quantity
100mg USD 50 In stock
200mg USD 80 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Atropine sulfate monohydrate is a competitive antagonist for the muscarinic acetylcholine receptor, used to decrease the production of saliva and secretions of the airway prior to surgery.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 694.83
Formula 2(C17H23NO3).H2O.H2SO4
CAS Number 5908-99-6
Purity >98%
Solubility 139 mg/mL in DMSO
Storage at -20°C
References

Catalytic activity of ruthenium(III) on the oxidation of an anticholinergic drug-atropine sulfate monohydrate by copper(III) periodate complex in aqueous alkaline medium - decarboxylation and free radical mechanism.
Byadagi KS, et al. Acta Chim Slov. 2013;60(3):617-27. PMID: 24169716.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Atropine Sulfate Monohydrate , Atropine sulfate hydrate supplier, AChE, inhibitors

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