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Aniracetam

Cat. No. M2243
Aniracetam Structure
Synonym:

Draganon, Sarpul

Size Price Availability Quantity
10mM*1mL in DMSO USD 55  USD55 In stock
500mg USD 50  USD50 In stock
1g USD 75  USD75 In stock
2g USD 120  USD120 In stock
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Quality Control & Documentation
Biological Activity

Aniracetam is a compound that promotes intellectual development and neuroprotection.

Chemical Information
Molecular Weight 219.24
Formula C12H13NO3
CAS Number 72432-10-1
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Said Abd El-Monem Hassan, et al. Spectrofluorimetric study on fluorescence quenching of tyrosine and l-tryptophan by the aniracetam cognition enhancer drug: quenching mechanism using Stern-Volmer and double-log plots

[2] Hannah Phillips, et al. Aniracetam does not improve working memory in neurologically healthy pigeons

[3] Thomas W Elston, et al. Aniracetam does not alter cognitive and affective behavior in adult C57BL/6J mice

[4] Kazuo Nakamura. Aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries

[5] C R Lee, et al. Aniracetam. An overview of its pharmacodynamic and pharmacokinetic properties, and a review of its therapeutic potential in senile cognitive disorders

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Keywords: Aniracetam, Draganon, Sarpul supplier, AChR/AChE, inhibitors, activators


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