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AMPPD

Cat. No. M9037
AMPPD Structure
Synonym:

Lumigen PPD

Size Price Availability Quantity
5mg USD 40  USD40 In stock
10mg USD 60  USD60 In stock
25mg USD 100  USD100 In stock
50mg USD 140  USD140 In stock
100mg USD 180  USD180 In stock
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Quality Control & Documentation
Biological Activity

AMPPD is a new biochemistry ultrasensitive alkaline phosphatase substrate.

Chemical Information
Molecular Weight 382.34
Formula C18H23O7P
CAS Number 122341-56-4
Solubility (25°C) Water: ≥ 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Tu L, et al. Phys Chem Chem Phys. Spectroscopic study of the authentic emitter of AMPPD chemiluminescence in alkaline aqueous solution.

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