Free shipping on all orders over $ 500

Alfuzosin

Cat. No. M5395
Alfuzosin   Structure
Synonym:

SL 77499

Size Price Availability Quantity
10mg USD 60 In stock
50mg USD 180 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Alfuzosin is an α1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH).

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 389.45
Formula C19H27N5O4
CAS Number 81403-80-7
Purity >98%
Solubility 10mM in DMSO
Storage at -20°C
References

Efficacy and Safety of Alfuzosin as Medical Expulsive Therapy for Ureteral Stones: A Systematic Review and Meta-Analysis.
Liu C, et al. PLoS One. 2015 Aug 5;10(8):e0134589. PMID: 26244843.

Related Androgen Receptor Products
Dehydroepiandrosterone

Dehydroepiandrosterone is an effective antiapoptotic factor.

ASC-J9

ASC-J9, also known as GO-Y025 and Dimethylcurcumin, suppressesing castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors.

GSK-2881078

GSK 2881078 is a selective androgen receptor modulator potentially for the treatment of cachexia. GSK 2881078 is a selective androgen receptor modulator (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting to improve their physical function.

Indacaterol

Indacaterol(Onbrez; Arcapta) is an ultra-long-acting β-adrenoceptor agonist.

Nandrolone phenylpropionate

Nandrolone phenylpropionate (NPP) is an anabolic-androgenic steroid. The low androgenicity and enhanced anabolic activity of NPP has shown to positively influence calcium metabolism and to increase bone mass in osteoporosis.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Alfuzosin , SL 77499 supplier, Androgen Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.