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ABTS diammonium salt

Cat. No. M13765
ABTS diammonium salt Structure
Synonym:

AzBTS-(NH4)2

Size Price Availability Quantity
500mg USD 40  USD40 In stock
1g USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.

Chemical Information
Molecular Weight 548.68
Formula C18H24N6O6S4
CAS Number 30931-67-0
Solubility (25°C) Water ≥ 40 mg/mL
Storage 2-8°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Hong Liu, et al. Food Sci Nutr. Novel green soybean shuidouchi fermented by Bacillus velezensis with multibioactivities

[2] Mădălina Maria Nichitoi, et al. Sci Rep. Polyphenolics profile effects upon the antioxidant and antimicrobial activity of propolis extracts

[3] Margherita Lavorgna, et al. Foods. Theobromacacao Criollo var. Beans: Biological Properties and Chemical Profile

[4] Laura Rojas Lorz, et al. Int J Mol Sci. Anti-Wrinkling and Anti-Melanogenic Effect of Pradosia mutisii Methanol Extract

[5] Pierluigi Plastina, et al. Nutrients. In Vitro Anti-Inflammatory and Radical Scavenging Properties of Chinotto ( Citrus myrtifolia Raf.) Essential Oils

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