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Cat. No. M9791
5-Ethynyl-2'-deoxyuridine Structure


Size Price Availability Quantity
50mg USD 37 In stock
100mg USD 64 In stock
500mg USD 230 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 252.22
Formula C11H12N2O5
CAS Number 61135-33-9
Purity >98%
Solubility DMSO ≥ 60 mg/mL
Storage 2-8°C, protect from light, dry, sealed

Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy dvrgs
Sainan An, et al. EBioMedicine. 2018 Oct;36:553-562. PMID: 30224312.

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Abmole Inhibitor Catalog 2017

Keywords: 5-Ethynyl-2'-deoxyuridine, Edu supplier, inhibitors

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