Free shipping on all orders over $ 500

5-Ethynyl-2'-deoxyuridine

Cat. No. M9791
5-Ethynyl-2'-deoxyuridine Structure
Synonym:

Edu

Size Price Availability Quantity
50mg USD 37 In stock
100mg USD 64 In stock
500mg USD 230 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 252.22
Formula C11H12N2O5
CAS Number 61135-33-9
Purity >98%
Solubility DMSO ≥ 60 mg/mL
Storage 2-8°C, protect from light, dry, sealed
References

Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy dvrgs
Sainan An, et al. EBioMedicine. 2018 Oct;36:553-562. PMID: 30224312.

Related Products
Desmopressin Acetate

Desmopressin is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock.

Iron dextran

Iron dextran (Fe dextran) is used in the study of iron-deficiency anemia.

nor-NOHA acetate

nor-NOHA acetate is a specific and reversible inhibitor of rat liver arginase.

SFLLRNPNDKYEPF

Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe is a synthetic thrombin receptor agonist peptide.

AZ-33

AZ-33 is a potent lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.5 μM.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: 5-Ethynyl-2'-deoxyuridine, Edu supplier, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.