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5-BrdU

Cat. No. M6348
5-BrdU Structure
Synonym:

BUdR; BRDU

Size Price Availability Quantity
100mg USD 55 In stock
500mg USD 100 In stock
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Quality Control
Biological Activity

5-BrdU is a synthetic thymidine analog; incorporated into DNA during replication. 5-BrdU (Bromodeoxyuridine) is used in assays for cell proliferation.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 307.1
Formula C9H11BrN2O5
CAS Number 59-14-3
Purity 99.47%
Solubility DMSO 30 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: 5-BrdU, BUdR; BRDU supplier, DNA/RNA Synthesis, inhibitors

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