5-BrdU is a synthetic thymidine analog; incorporated into DNA during replication. 5-BrdU (Bromodeoxyuridine) is used in assays for cell proliferation.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||DMSO 30 mg/mL|
|Related DNA/RNA Synthesis Products|
COH29 is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity.
Plicamycin, also known as mithramycin or Mithramycin A is a n antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity.
GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
|Pyridostatin Trifluoroacetate Salt
Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer, with a Kd of 490 nM.
Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity.
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