2,6-Dichloro-3,5-dimethoxyaniline is H3B-6275 intermediate.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||10 mM in DMSO|
|2-Chloro-5- nitro-benzeneacetic acid|
FX1 is a potent and specific BCL6 inhibitor, with an IC50 of around 35 μM.
GC376 is a 3CLpro inhibitor; inhibits the replication of viruses TGEV, FIPV and PTV with IC50 values of 0.15, 0.2 and 0.15 μM.
AVex-73 hydrochloride is a Sigma-1 Receptor agonist with an IC50 of 860 nM.
Tropifexor is a novel and highly potent agonist of farnesoid X receptor (FXR).
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