Free shipping on all orders over $ 500


Cat. No. M6106
17α-Methyltestosterone Structure

Methyltestosterone; 17-Methyltestosterone

Size Price Availability Quantity
100mg USD 100 In stock
Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

17α-meT is a Class III AAS with an alkylation at C-17 and with restricted potential of metabolizing substrates for aromatization. In fact, 17α-meT cannot be aromatize to 17β-estradiol, the most potent form of mammalian estrogenic steroids, and the main product of aromatase. A single injection of 17α-meT immediately before the footshock produced significant impairment of inhibitory avoidance learning in males but not females. Our results show that exposure to a single pharmacological dose of 17α-meT during periadolescence exerts sex-specific cognitive effects without affecting anxiety.

Cell Experiment
Cell lines
Preparation method
Incubation time
Animal Experiment
Animal models Gonadally-intact male and female Sprague Dawley rats
Formulation 0.9% saline containing 30% cyclodextrin
Dosages 7.5 mg/kg
Administration i.p.
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 302.45
Formula C20H30O2
CAS Number 58-18-4
Purity >99%
Solubility 10 mM in DMSO
Storage at -20°C

Synthesis and chemical reactions of the steroidal hormone 17α-methyltestosterone.
El-Desoky el-SI, et al. Steroids. 2016 Jan;105:68-95. PMID: 26639430.

Sex-specific effect of the anabolic steroid, 17α-methyltestosterone, on inhibitory avoidance learning in periadolescent rats.
Ramos-Pratts K, et al. Behav Processes. 2013 Oct;99:73-80. PMID: 23792034.

Related Androgen Receptor Products
Nandrolone phenylpropionate

Nandrolone phenylpropionate (NPP) is an anabolic-androgenic steroid. The low androgenicity and enhanced anabolic activity of NPP has shown to positively influence calcium metabolism and to increase bone mass in osteoporosis.

ChlordehydroMethyl Testosterone

Testosterone is normally present in the circulation of both men and women. Due to the dynamic regulation of endogenous testosterone production, including the acute effects of competition and exercise, testosterone concentrations may vary considerably within and among individuals.

Testosterone phenylpropionate

Testosterone phenylpropionate is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester.

Testosterone isocaproate

Testosterone Isocaproate help in increasing the body weight and will also help in gaining the strength and also help in losing fat in the body and gives an increase in libido, red blood cells, stamina and quick recovery after heavy training.

Testosterone Enanthate

Androcur-treatment abolished testosterone-reduced cAMP, coupled with a changed expressional milieu of cAMP signaling elements. Results from in vitro experiments suggest that some of these effects are testosterone-AR dependent, while others could be due to disturbed LH and/or other signals.

Abmole Inhibitor Catalog 2017

Keywords: 17α-Methyltestosterone, Methyltestosterone; 17-Methyltestosterone supplier, Androgen Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.