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12-O-tetradecanoyl-phorbol-13-acetate

Cat. No. M4647
12-O-tetradecanoyl-phorbol-13-acetate Structure
Size Price Availability Quantity
2mg USD 70 In stock
5mg USD 110 In stock
10mg USD 150 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

12-O-tetradecanoyl-phorbol-13-acetate

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 616.83
Formula C36H56O8
CAS Number 16561-29-8
Purity >99%
Solubility DMSO 20 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: 12-O-tetradecanoyl-phorbol-13-acetate supplier, PKC, inhibitors

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