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1-methoxy PMS

Cat. No. M9244
1-methoxy PMS Structure
Size Price Availability Quantity
50mg USD 86 In stock
100mg USD 135 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

1-methoxy PMS is stable electron-transport mediator between NAD(P)H and tetrazolium dyes. 1-methoxy PMS can induce active oxygen formation.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 336.36
Formula C15H16N2O5S
CAS Number 65162-13-2
Purity >98%
Solubility DMSO: ≥ 20 mg/mL (Need warming and ultrasonic)
Storage 4°C, protect from light
References

Tools for mass screening of G6PD deficiency: validation of the WST8/1-methoxy-PMS enzymatic assay in Uganda.
De Niz M, et al. Malar J. 2013 Jun 19;12:210. PMID: 23782846.

Chemiluminescence assay for tetrahydrobiopterin based on the generation of hydrogen peroxide using isoluminol-microperoxidase in the presence of 1-methoxy PMS.
Arakawa H, et al. Luminescence. 2007 May-Jun;22(3):245-50. PMID: 17285567.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: 1-methoxy PMS supplier, inhibitors

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