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1,4-Bis(aminomethyl)benzene

Cat. No. M10053
1,4-Bis(aminomethyl)benzene Structure
Synonym:

p-XylylenediaMine

Size Price Availability Quantity
100mg USD 60  USD60 In stock
1g USD 90  USD90 In stock
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Quality Control & Documentation
Biological Activity

1,4-Bis(aminomethyl)benzene is used in epoxy resin, photosensitive nylon, polyurethane coatings, etc.

Chemical Information
Molecular Weight 136.19
Formula C8H12N2
CAS Number 539-48-0
Solubility (25°C) Soluble in water
Storage RT, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yongzhuang Liu, et al. ACS Sustain Chem Eng. Primary Benzylamines by Efficient N-Alkylation of Benzyl Alcohols Using Commercial Ni Catalysts and Easy-to-Handle Ammonia Sources

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Keywords: 1,4-Bis(aminomethyl)benzene, p-XylylenediaMine supplier, inhibitors, activators


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