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1,3-Benzoxazole-6-carboxylic acid

Cat. No. M10426
1,3-Benzoxazole-6-carboxylic acid Structure
Size Price Availability Quantity
10mg USD 88.2  USD98 In stock
50mg USD 237.6  USD264 In stock
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Quality Control
  • Current batch:
  • Purity >97%
  • COA
  • MSDS
Biological Activity

1,3-Benzoxazole-6-carboxylic acid

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 163.13
Formula C8H5NO3
CAS Number 154235-77-5
Purity >97%
Solubility
Storage 2-8°C, dry, sealed
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  Catalog
Abmole Inhibitor Catalog 2017




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