| Cat.No. | Name | Information |
|---|---|---|
| M3386 | Amiloride hydrochloride | Amiloride hydrochloride, a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. |
| M3366 | Amiloride hydrochloride dihydrate | Amiloride Hydrochloride Dihydrate (MK-870 Hydrochloride Dihydrate) is an inhibitor of epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride dihydrate is polycystin-2 (PC2; TRPP2) channel blocker. |
| M4068 | Ginsenoside-Rg3 | 20(S)-Ginsenoside Rg3 is the main ingredient of red ginseng. 20(S) -ginsenoside Rg3 inhibited Na+ and hKv1.4 channels with IC50 of 32.2±4.5 and 32.6±2.2 μM, respectively. 20(S) -ginsenoside Rg3 also inhibited Aβ, NF-κB activity and COX-2 expression. |
| M4020 | Bulleyaconi-cine-A | Bulleyaconitine A, A compound isolated from aconite, has anti-inflammatory activity and can also be used in pain relief studies. |
| M3987 | Ginsenoside Rb1 | Ginsenoside Rb1 is an ingredient in the Chinese medicine Panax ginseng. Ginsenoside inhibition Na, K-ATPase++ activityIC50 6.3±1.0 μM. Ginsenoside Rb1 also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. |
| M3935 | Digoxin | Digoxin is a potent inhibitor of Na+/K+-ATPase, has the potential for arrhythmia and heart failure. |
| M3436 | Furosemide | Furosemide is a tabular diuretic used in studies of congestive heart failure and edema. |
| M3412 | Propafenone hydrochloride | Propafenone HCl is a sodium-channel blocker that also has a high affinity for β-receptors (IC50 = 32 nM). It blocks transient outward potassium current (Ito) and sustained delayed rectifier K+ current (Isus) with IC50 values of 4.9 μM and 8.6 μM, respectively.In addition, Propafenone inhibits the proliferation of esophageal cancer by inducing mitochondrial dysfunction and apoptosis. |
| M3358 | Procainamide hydrochloride | Procainamide hydrochloride is a sodium channel blocker, and also a DNA methyltransferase inhibitor. |
| M3354 | Carbamazepine | Carbamazepine is a sodium channel inhibitor with an IC50 of 131 μM when treated with synaptosomes in rat brain. It can be used in trigeminal neuralgia research. |
| M3349 | Methocarbamol | Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. |
| M3175 | Meticrane | Meticrane is a diuretic agent. |
| M3158 | Chloroprocaine hydrochloride | Chloroprocaine hydrochloride is a local anesthetic during surgical procedures. |
| M3083 | Triamterene | Triamterene blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner with IC50 of 4.5 μM. |
| M2961 | Procaine hydrochloride | Procaine is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM. *The compound is unstable in solutions, freshly prepared is recommended |
| M2908 | Oxybuprocaine hydrochloride | Oxybuprocaine hydrochloride is a local anesthetic, which is used especially in ophthalmology and otolaryngology. |
| M2847 | Mexiletine hydrochloride | Mexiletine hydrochloride belongs to Class IB anti-arrhythmic group of medicines, inhibits sodium channels to reduce the inward sodium current. |
| M2802 | Lamotrigine | Lamotrigine is a novel anticonvulsant compound for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, and also is a sodium channel blocker. |
| M2645 | Disopyramide Phosphate | Dipiramide (DISO) is a class 1A antiarrhythmic compound widely used in the study of ventricular and supraventricular arrhythmias. |
| M2530 | Clopamide | Clopamide is an orally active thiazide-like diuretic agent that inhibits the sodium-coupled chloride cotransporter SLC12A3. |
| M2513 | Chlorthalidone | Chlorthalidone is a thiazide-like diuretic, it has potential for the research of hypertension. |
| M2511 | Chlorpropamide | Chlorpropamide is a sulfonylurea compound used to study non-insulin-dependent diabetes mellitus (NIDDM). |
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