| Cat.No. | Name | Information |
|---|---|---|
| M3386 | Amiloride hydrochloride | Amiloride hydrochloride, a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. |
| M3366 | Amiloride hydrochloride dihydrate | Amiloride Hydrochloride Dihydrate (MK-870 Hydrochloride Dihydrate) is an inhibitor of epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride dihydrate is polycystin-2 (PC2; TRPP2) channel blocker. |
| M8004 | Phenamil methanesulfonate salt | Phenamil methanesulfonate is an irreversible inhibitor of amiloride-sensitive Na+ channels; derivative of amiloride. |
| M7552 | ETH2120 | Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc. |
| M7520 | Brivaracetam | Brivaracetam (UCB 34714) is chemically related to levetiracetam (LEV, Keppra). It possesses a binding affinity for the synaptic vesicle protein 2A (SV2A) ten-fold above that of LEV and also shows an ability to inhibit Na+ channels. |
| M7288 | SEA 0400 | SEA 0400 is a potent Na +/Ca 2+ exchanger (NCX) inhibitor. |
| M7180 | QX 314 bromide | QX 314 bromide is a na+ channel blocker. |
| M6755 | GMQ hydrochloride | GMQ hydrochloride is a potent and selective modulator of acid-sensing ion channel (ASIC) that activates ASIC3 channels under neutral pH. GQM blocks acid-induced maximal peak current and alters ASICs pH dependence for activation and inactivation. |
| M6498 | Benzamil | Benzamil is a nCX inhibitor, Deg/ENaC channel blocker; amiloride derivative. |
| M6342 | 4-Chlorophenylguanidine hydrochloride | 4-Chlorophenylguanidine hydrochloride is a urokinase inhibitor. |
| M6085 | GSK-1014802 | CNV1014802(GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor. |
| M6068 | Zonisamide | Zonisamide is an fDA-approved antiepileptic compound that blocks voltage-dependent sodium (+) and T-type calcium channels. |
| M6054 | Vinpocetine | Vinpocetine is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia and Alzheimer's disease. |
| M5943 | Rufinamide | Rufinamide is a voltage-gated sodium channel blocker, used an anticonvulsant medication. |
| M5904 | Proparacaine HCl | Proparacaine HCl is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM. |
| M5876 | Phenytoin Sodium | Phenytoin Sodium is a potent Voltage-gated Na+ channels (VGSCs) blocker. |
| M5875 | Phenytoin | Phenytoin is an inactive voltage-gated sodium channel stabilizer. |
| M5699 | Ibutilide fumarate | Ibutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells. |
| M5069 | S0859 | S0859 is an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM). |
| M4765 | Oleandrin | Oleandrin (PBI-05204) inhibited Na+, K+ -atPase activity with IC50 of 620 nM. |
| M4339 | Bufalin | Bufalin is a potent Na+/K+-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, 45 and 40 nM respectively, it has anti-cancer activity. |
| M4148 | Dimethyl-lithospermate-B | Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist. Dimethyl lithospermate B slows sodium current (INa) inactivation, resulting in an early increase in inward current of the action potential (AP). |
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