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  Catalog
Abmole Inhibitor Catalog 2017

IL Receptor/Related Interleukin Receptor/Related

Inhibitors

Cat.No.  Name Information
M10559 Tyrphostin A1 Tyrphostin A1 is a weaker EGFR tyrosine kinase inhibitor, Tyrphostin A1 inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells.
M10159 Kaempferol 3-O-β-D-glucuronide Kaempferol 3-O-β-D-glucuronide is a conjugated kaempferol metabolite, which has anti-inflammatory effect.
M10139 Anakinra Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R.
M9868 GIBH-130 GIBH-130 is a neuroinflammation inhibitor, with IC50 value of 3.4 nM for suppressing the IL-1β secretion by activated microglia.
M6258 CA-4948 CA-4948 is a reversible kinase inhibitor that modulates IRAK4 function in both the toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling cascades, and demonstrates pharmacodynamic and antitumor activity in in vitro and in vivo nonclinical models.
M3814 Sarilumab Sarilumab is a human recombinant IgG1 antibody that binds to both forms of interleukin 6 receptors (IL-6R), thus inhibiting the IL-6-mediated signaling.
M2626 Dexamethasone Sodium Phosphate Dexamethasone is an interleukin receptor inhibitor and also suppresses COX-2.
M1622 Secukinumab Secukinumab is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A.
M1621 Ustekinumab Ustekinumab is a human monoclonal antibody directed against interleukin 12 and interleukin 23, naturally occurring proteins that regulate the immune system and immune-mediated inflammatory disorders.


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