| Cat.No. | Name | Information |
|---|---|---|
| M25413 | Fucoxanthin | Fucoxanthin is a carotenoid that occurs naturally in certain algae with anti-obesity, anti-oxidant, anti-diabetic, anticancer and anti-inflammatory activities. |
| M20413 | 4-Biphenylacetic acid | 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors. |
| M10093 | α-Galactosyl Ceramide | α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) is a potent NKT cell stimulator and selective CD1d ligand. α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. |
| M9358 | ITE | ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), which directly binding to AHR with a Ki of 3 nM. |
| M4614 | Orientin | Orientin |
| M1831 | Cyclosporine A | Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. cyclosporin A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. |
| M54780 | Naringenin | Naringenin is the predominant flavanone in Citrus reticulata Blanco, it displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity. |
| M21680 | TJ-M2010-5 | TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain of MyD88 to interfere with its homodimerization, and the TLR/MyD88 signal pathway. |
| M20958 | Talniflumate | Talniflumate is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma. |
| M20433 | Tolmetin | Tolmetin is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity. |
| M20432 | 5-Acetylsalicylic acid | 5-Acetylsalicylic acid is an aminosalicylate anti-inflammatory agent, which has anti-inflammatory and is considered to be the active agent in inflammatory bowel disease (IBD). |
| M20412 | NLRP3 Inflammasome Inhibitor I | NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome. |
| M18258 | 11beta,13-Dihydrolactucin | 11beta,13-Dihydrolactucin is a sesquiterpene lactone obtained by formal hydrogenation across the 11,13-double bond of lactucin. Found in chicory It has a role as a plant metabolite. |
| M16307 | Isogosferol | Isogosferol is a potent anti-inflammatory agent. Isogosferol decreases LPS-stimulated NO and IL-1β expression. Isogosferol decreases the LPS-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2. |
| M14095 | T6167923 | T6167923 is a potent and selective inhibitor of MyD88-dependent signaling pathways. |
| M11481 | Abatacept | Abatacept is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1. Abatacept binds to antigen presenting cells CD80 and CD86, blocks costimulatory signals and inhibits T cell activation, and is used in the study of rheumatoid arthritis and juvenile rheumatoid arthritis. |
| M10981 | Thymol | Thymol is the main monoterpene phenol present in essential oils, which are isolated from plants belonging to the family Lipaceae and other plants such as Verbenaiaceae, Psylliaceae, Buttercupaceae, etc. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects. |
| M10924 | LY-3475070 | Ly-3475070 is the first oral bioavailable, selective and extracellular enzyme CD73 (cluster of Differentiation 73, 5'-ecto-nucleotidase, 5' -nt, Ecto -5'-nucleotidase) inhibitor. |
| M10772 | AB-680 | AB-680 is a potent, reversible, selective CD73 (extracellular nucleotide enzyme) inhibitor of hCD73 Ki The value is 4.9 pM, which is more than 10,000 times more selective than the associated extracellular nucleotide CD39. Has antitumor activity. |
| M10573 | (+/-)-Lisofylline | (±)-Lisofylline is a potent anti-inflammatory agent in which only the (-) optical isomer is biologically active. (±)-Lisofylline was found to inhibit the generation of phosphatidic acid from cytokine-activated lysophosphatidic acyl transferase. |
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