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Cuproptosis Cuproptosis

Inhibitors

Cat.No.  Name Information
M11307 8-Hydroxyquinoline 8-hydroxyquinoline is a mono-proton bicyclic chelator that is used as a preservative, disinfectant, and insecticide and as a transcription inhibitor. It is a preservative with mild fungal, bacterial, repellent and amoeba killing properties. It is a strong copper ion-carrier and can be used in copper death (Cuproptosis) research.
M3390 Disulfiram Disulfiram is used in the study of chronic alcoholism, with acute sensitivity to alcohol, and is a potent copper ion-carrier that can be used in cuproptosis studies.
M3137 Zinc Pyrithione Zinc Pyrithione is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death (cuproptosis) studies.
M2891 NSC 319726 NSC 319726 is a p53(R175) mutant activator that inhibits the growth of p53(R175) mutant cells and acts on p53(R175) mutant cells with IC50 of 8 nM, which has no inhibition on p53 wild-type cells. NSC 319726 is a potent copper ion-carrier that can be used in cuproptosis studies.
M2083 Elesclomol Elesclomol (STA-4783) is a novel oxidative stress inducer that acts on tumor cells and promotes their apoptosis, and is a strong copper ion-carrier that can be used for cuproptosis studies.



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