Cat.No. | Name | Information |
---|---|---|
M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
M9058 | Varenicline hydrochloride | Varenicline hydrochloride is a potent partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR, with EC50s of 2.3 μM and 55 μM, respectively. In addition, Varenicline hydrochloride is also a potent full agonist of α7 nAChRs. In addition, Varenicline hydrochloride is a potent full α7 nAChRs agonist with an EC50 of 18 μM. |
M8888 | Donepezil | Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively. |
M8846 | VU0238429 | VU0238429 is a selective muscarinic acetylcholine receptor 5 (M5) positive allosteric modulator; causes leftward shift in acetylcholine potency. |
M8342 | AF-DX 116 | AF-DX 116 is a selective M2 muscarinic acetylcholine receptor antagonist. |
M8303 | Azimilide dihydrochloride | Azimilide is an investigational class III anti-arrhythmic compound that blocks fast and slow components of the delayed rectifier cardiac potassium channels. |
M8028 | Propantheline bromide | Propantheline bromide is an orally active mAChR antagonist that inhibits acetylcholine action at postganglionic synapses, and can be used in studies related to smooth muscle dysfunction as well as gastrointestinal spasms. |
M7940 | Mecamylamine hydrochloride | Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier. |
M7853 | Ipratropium bromide monohydrate | Nonselective muscarinic acetylcholine receptor antagonist; bronchodilator. |
M7585 | Atropine | Atropine (Tropine tropate) is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia. |
M7517 | Acotiamide hydrochloride | Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor. |
M7472 | VU 0365114 | VU 0365114 is a positive allosteric modulator of M5 receptors. |
M7227 | EVP-6124 hydrochloride | EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). |
M7141 | Pirenzepine dihydrochloride | Pirenzepine dihydrochloride is a selective M1 muscarinic antagonist. |
M6941 | McN-A 343 | McN-A 343 is a selective M 1 muscarinic agonist. |
M6350 | 5-Methylfurmethiodide | 5-Methylfurmethiodide is a potent muscarinic agonist. |
M6341 | 4-Acetyl-1,1-dimethylpiperazinium iodide | 4-Acetyl-1,1-dimethylpiperazinium iodide is a nicotinic agonist. |
M6335 | 3-Bromocytisine | 3-Bromocytisine is a potent agonist of α4β4, α4β2 and α7 nACh receptors. |
M6273 | Varenicline tartrate | Varenicline Tartrate is a nicotinic AChR partial agonist, used to treat nicotine addiction. |
M6268 | Varenicline | Varenicline (CP 526555) is a selective α4β2 nicotinic receptor partial agonist, it stimulates nicotine receptors more weakly than nicotine itself does. |
M6127 | TD-4208 | TD-4208 is a novel and potent muscarinic receptor antagonist that has a high affinity and long residence time at the M3 receptor, and demonstrates in vitro kinetic selectivity for M3 over M2 muscarinic receptor subtype and no meaningful off-target activity. |
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