Certificate of Analysis

 

Product Name: XL647
Catalog Number: M3780
CAS Number: 781613-23-8 (874286-84-7)

Physical and Chemical Properties
Formula: C24H25Cl2FN4O2
Molecular Weight: 491.39
Solubility: DMSO 3 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: XL647 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: XL647 is an extremely potent and selective inhibitor of EGFR phosphorylation (IC50 = 0.3 nM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.